Hepatitis B – What is Hepatitis B? | Hepatitis B Definition

Hepatitis B is an infectious illness caused by hepatitis B virus (HBV) which infects the liver of hominoidae, including humans, and causes an inflammation called hepatitis. Originally known as “serum hepatitis”, the disease has caused epidemics in parts of Asia and Africa, and it is endemic in China. About a third of the world’s population, more than 2 billion people, have been infected with the hepatitis B virus. This includes 350 million chronic carriers of the virus. Transmission of hepatitis B virus results from exposure to infectious blood or body fluids.

The acute illness causes liver inflammation, vomiting, jaundice and rarely death. Chronic hepatitis B may eventually cause liver cirrhosis and liver cancer a fatal disease with very poor response to current chemotherapy. The infection is preventable by vaccination.

Hepatitis B virus is an hepadnavirus hepa from hepatotrophic and dna because it is a DNA virus and it has a circular genome composed of partially double stranded DNA. The viruses replicate through an RNA intermediate form by reverse transcription, and in this respect they are similar to retroviruses. Although replication takes place in the liver, the virus spreads to the blood where virus specific proteins and their corresponding antibodies are found in infected people. Blood tests for these proteins and antibodies are used to diagnose the infection.

Hepatitis B is a potentially life-threatening liver infection caused by the hepatitis B virus. It is a major global health problem and the most serious type of viral hepatitis. It can cause chronic liver disease and puts people at high risk of death from cirrhosis of the liver and liver cancer.

Worldwide, an estimated two billion people have been infected with the hepatitis B virus (HBV), and more than 350 million have chronic (long-term) liver infections.

A vaccine against hepatitis B has been available since 1982. Hepatitis B vaccine is 95% effective in preventing HBV infection and its chronic consequences, and is the first vaccine against a major human cancer.

Hepatitis is an inflammation of the liver. Inflammation causes soreness and swelling. Hepatitis can be caused by many things. Hepatitis is most commonly caused by one of the 5 hepatitis viruses (A, B, C, D or E). All types of hepatitis cause inflammation of the liver, which interferes with its ability to function. Lack of blood supply to the liver, poison, autoimmune disorders, excessive alcohol use, an injury to the liver and taking certain medicines can also cause hepatitis. Less commonly, viral infections such as mononucleosis or cytomegalovirus can cause hepatitis.

There are 2 main kinds of hepatitis, acute hepatitis (short-lived) and chronic hepatitis (lasting at least 6 months). If you have acute hepatitis, the liver might become inflamed very suddenly and you might have nausea, vomiting, abdominal pain, fever and body aches. Or you may not experience any symptoms. Most people get over the acute inflammation in a few days or a few weeks.

Sometimes, however, the inflammation doesn’t go away. When the inflammation doesn’t go away in 6 months, the person has chronic hepatitis.

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